Monitor Closely (1)fosamprenavir increases levels of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Inhaled Corticosteroids: Are considered the most effective long-term usage medication for control and management of asthma. Increased risk of Cushing's syndrome or adrenal suppression. 1 puff per day. There may be variations in CSA schedules between individual states. Flovent and HFA are both used to treat asthma and breathing difficulties brought about by COPD, but they work differently. Others are systemic, meaning they stem from the medication circulating through your body. If you have specific questions regarding a drugs safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information. 0 4-11 years old Increases riak for systemic corticosteroid side effects. Are Flovent Diskus and Asmanex the Same Thing? Fluticasone Propionate and Salmeterol inhalation powder, WIXELA INHUB 2 inhalations twice a day. Generic You take this bronchodilator daily in pill form to treat mild asthma. When you take a corticosteroid, your body detects high levels of the hormone and stops producing it, effectively "taking its foot off the accelerator.". Asmanex TWISTHALER 110 mcg: delivers 100 mcg mometasone furoate from the mouthpiece. Increases riak for systemic corticosteroid side effects. What Are Possible Side Effects of Flovent Diskus? Use Caution/Monitor. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Use Caution/Monitor. Prescribed for Eosinophilic Esophagitis, Asthma - Maintenance, Bronchopulmonary Dysplasia. See also: Flovent HFA side effects in more detail. As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Use Caution/Monitor. Flonase is a brand which is expensive but can be obtained as generic fluticasone on prescription. Talk to your healthcare provider before stopping your medication for any reason. Use Caution/Monitor. Consult your doctor for specific advice. Journal of Allergy and Clinical Immunology. You may need to use these medications for several months before you get their maximum benefit. Immunology and Allergy Clinics of North America. Advair is generally reserve Advair has two medications in it, an inhaled steroid (ICS) and a long acting bronchodilator (LABA). mometasone inhaled increases toxicity of chlorthalidone by Other (see comment). Low 200 mcg daily in evening Med 200 mcg bid or 400 mcg daily in the evening High 400 mcg bid . They typically are the preferred treatment for people with asthma who need more than a rescue inhaler can offer. Use Caution/Monitor. 1 puff twice a day. View all You might need regular blood tests to make sure you're getting the correct dose. Ipratropium (Atrovent HFA) is a short-acting bronchodilator that's usually prescribed for emphysema or chronic bronchitis but is sometimes used to treat asthma attacks. 100/50, 250/50, 500/50 (generic formulation) Symbicort 80/4.5: Increased risk of Cushing's syndrome or adrenal suppression. ArmonAir RespiClick 55 mcg Fluticasone furoate, Umeclidinium, and Vilanterol inhalation powder, Trelegy Ellipta Ordered Substituted with Flovent . 100/62.5/25 mcg Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: current/past infections (such as tuberculosis, herpes), bone loss (osteoporosis), eye problems (such as cataracts, glaucoma).If you have switched from a corticosteroid taken by mouth (such as prednisone tablets) to this inhaler within the past 12 months, or if you have been using this product in higher-than-usual doses for a long time, it may be more difficult for your body to respond to physical stress. However, poorly controlled asthma can also slow down growth. Increased risk for Cushing syndrome and adrenal suppression. Biologics reduce inflammation by targeting immune system antibodies or specific cells. information and will only use or disclose that information as set forth in our notice of What is the difference between flovent and ventolin 90 mcg inhaler? This narrows them and makes it hard to breathe. Comment: Corticosteroids may increase hypokalemic effect of loop diuretics. 404 0 obj <>/Filter/FlateDecode/ID[<4F115DB637880542963206AEE7D53A80><6A89A34F6B8DF34096C518B0FCF43ACC>]/Index[384 37]/Info 383 0 R/Length 98/Prev 629632/Root 385 0 R/Size 421/Type/XRef/W[1 2 1]>>stream Manage and view all your plans together even plans in different states. You generally receive injections once a week for a few months, and then once a month for 3 to 5 years. Comment: Corticosteroids may enhance the hyponatremic effect of intranasal desmopressin. Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. 1-2 puffs of 40 or 80 twice a day. Leukotriene modifiers can help prevent symptoms for up to 24 hours. The dose of Asmanex HFA is 2 puffs in the morning and 2 puffs in the evening. Increased risk for Cushing syndrome and adrenal suppression. Asmanex Twisthaler is indicated for the maintenance treatment of asthma as prophylactic therapy in patients 4 years of age and older. 0.5 mg/2mL susp Symptoms of asthma recur more than twice a week. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. See additional information. Maintenance/control of asthma and COPD. ), your immune system releases cells that cause inflammation in your bronchial tubes (airways). National Heart, Lung, and Blood Institute. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. When used every day, Flovent (fluticasone) can lower the number and severity of asthma attacks. Accessed May 13, 2022. Use Caution/Monitor. Do not wet the inhaler. For maintenance treatment and exacerbation reduction in COPD. This inhaler is used twice per day. Comment: Corticosteroids may enhance the hypokalemic effect of amphtericin B. . Salmeterol Can Fam Physician. 2011;111(11 Suppl 7):S11-S17. Use Caution/Monitor. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Monitor Closely (1)mometasone inhaled increases toxicity of deferasirox by Other (see comment). For some people, certain white blood cells, called eosinophils, build up within body tissues. It does not work right away and should not be used to relieve sudden asthma attacks. Do not use actuators from other products with the Asmanex HFA canister, Store in a dry place at 25C (77F); excursion between 15-30C (59-89F), Store at room temperature 20-25C (68-77F); excursions permitted to 15-30C (59-86F), Do not use or store near heat or open flame; exposure to temperatures <120F may cause bursting; never throw container into fire or incinerator. provider for the most current information. d Mometasone furoate studied in a different receptor system. Inhaled steroids come in three different types of devices: When choosing an inhaler, oneof the main considerations is how much of the drug exiting the inhaler is actually deposited in the air passages of the lungs. American Academy of Allergy, Asthma & Immunology. 20022068244-overviewDiseases & Conditions, encoded search term (mometasone inhaled (Asmanex Twisthaler%2C Asmanex HFA)) and mometasone inhaled (Asmanex Twisthaler, Asmanex HFA), 100 Best-Selling, Most Prescribed Branded Drugs Through March, 100 Most Prescribed, Best-Selling Branded Drugs Through September, Top 100 Most Prescribed, Top-Selling Drugs. 180 mcg twice a day. and formulary information changes. Asmanex Twisthaler Received bronchodilators alone or inhaled corticosteroids: 220 mcg PO inhaled once daily in evening; may increase to 220 mcg q12hr if needed Received PO corticosteroids: 440. Dulera contains the steroid mometasone and the LABA formoterol. 1. Treatment of moderate persistent asthma in adolescents and adults. 6.5 out of 10 from a total of RxList does not provide medical advice, diagnosis or treatment. Use Caution/Monitor. This does not necessarily make one better than the other. Controlling symptoms of asthma helps you maintain your normal activities and decreases time lost from work or school. All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. Asmanex HFA comes in 2 strengths. The inflammatory response in the pathogenesis of asthma. Here's what you need to know to sort out the main classes and numerous subtypes of asthma drugs. Advertising revenue supports our not-for-profit mission. This inhaler worked great for me until Advair entered the market. Use Caution/Monitor. Flovent (fluticasone propionate) and Asmanex HFA (mometasone furoate) are steroids used to prevent asthma attacks. This substance is called an allergen. Asthma is one of the most common chronic diseases in primary care. mometasone inhaled decreases effects of aldesleukin by Other (see comment). While both medications are used daily to control asthma, one is not better than the other. Increases riak for systemic corticosteroid side effects. 2020;146(6):1217-1270. doi:10.1016/j.jaci.2020.10.003. It affects more than 25 million people in the United States with a prevalence of 7.8% among adults and children. 3pi! mometasone inhaled and moxifloxacin both increase Other (see comment). 1 mg/2 mL susp Share cases and questions with Physicians on Medscape consult. This medication can be used to treat eosinophilic asthma or allergic asthma by reducing certain kinds of cytokines that cause inflammation. Available for Android and iOS devices. Accessed May 12, 2022. nirmatrelvir/ritonavir will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Age 6 and older. https://www.aaaai.org/Tools-for-the-Public/Conditions-Library/Allergies/SLIT-Treatment-for-Allergic-Rhinitis-Nothing-to-Sn. Flovent Diskus Flovent Diskus is indicated for the maintenance treatment of asthma as prophylactic therapy in patients aged 4 years and older. By clicking send, you acknowledge that you have permission to email the recipient with this information. When used regularly every day, inhalation corticosteroids decrease the number and severity of asthma attacks. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. This prescription medicine is used for the long-term treatment of asthma in people aged 4 years and older. 100/50 Muiser S, et al. SLIT treatment for allergic rhinitis: Nothing to sneeze about. comprised of an assembled plastic cap-activated dosing mechanism with dose counter, drug-product storage unit, drug-product formulation (135 mg), and mouthpiece, covered by a white screw cap that bears the product label. If this occurs, use your quick-relief inhaler and get medical help right away. Increased risk of Cushing's syndrome or adrenal suppression. 69% of reviewers reported a positive effect, while 23% reported a negative effect. If an asthma attack occurs, use your quick-relief inhaler (such as albuterol, also called salbutamol in some countries) as prescribed. Do not use the mometasone HFA actuator with any other inhalation drug product. mometasone inhaled increases toxicity of deferasirox by Other (see comment). Potential for increased toxicity. A combination of ipratropium and albuterol (Combivent) may sometimes be used to treat asthma. Treasure Island (FL): StatPearls Publishing. Diskus does 1 or 2 inhalations two times per day. What Are Possible Side Effects of Flovent? Monitor Closely (1)itraconazole will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Accessed May 12, 2022. Use Caution/Monitor. Use Caution/Monitor. Increases riak for systemic corticosteroid side effects. For this reason, LABAs are taken only in combination with an inhaled corticosteroid. (bronchodilator), Dulera Monitor Closely (1)saquinavir will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This means it is a anti-inflammatory type med that will take the inflammed part and calm it down. Flovent may interact with antifungal medicines or HIV/AIDS medicines. 48% of reviewers reported a positive experience, while 29% reported a negative experience. Reviews for Flovent Top reviews Most recent Most helpful High rating Low rating Long-acting muscarinic antagonists. Use Caution/Monitor. 2. Comment: Corticosteroids may interfere with antitumor effects of aldesleukin. Combination agents used to treat COPD are Combivent, Advair, Symbicort, Dulera, DuoNeb, BREO ELLIPTA, Stiolto Respimat, Bevespi Aerosphere, Utribron Neohaler, and ANORA ELLPTA. If you already have a high risk of any of these things, are concerned about them, or suspect you're experiencing one, talk to your healthcare provider. STORAGE: Store at room temperature. Use Caution/Monitor. Read our. If an LABA cannot be used, a LAMA along with an inhaled corticosteroid can be an option. Know when to adjust your medications, when to see your provider and how to recognize an asthma emergency. Trelegy Website (COPD) Confused about your asthma medications? In addition, the U.S. Food and Drug Administration (FDA) has issued a warning about a slightly increased risk of heart and brain blood vessel problems while taking this drug. Keep all medical and lab appointments. Tracking symptoms and side effects and adjusting your treatment based on changes is key to keeping your asthma symptoms under control. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Learn how we can help 2.5k views Answered >2 years ago Thank 4 thanks A 28-year-old female asked: Is flovent safe to use with autisitc children. AirDuo Digihaler Avoid or Use Alternate Drug. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. 1 puff per day. They can help with allergic symptoms such as a runny nose, itchy eyes, congestion, sneezing and sinus pressure, but aren't substitutes for asthma medications. 1-2 puffs once or twice daily then q4hrs PRN. Keep the canister in the case. Dr. Bernstein Joel answered. Potential for increased toxicity. By comparison, nebulizers can sometimes deliver results that are superior to either type of inhaler. There are several types of long-term control medications, including the following. Age 18 and older: Most 12 and above. Use Caution/Monitor. Copyright(c) 2023 First Databank, Inc. As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Learn when you can treat sudden breathing problems by yourself and when you must get medical help right away. Qvar 40 Redihaler Rarely, inhaled steroids can cause hives, swelling, and a rash that requires . What to Know About Pulmicort (Budesonide), The inflammatory response in the pathogenesis of asthma, The mode of action of anticholinergics in asthma, A review on the safety and efficacy of inhaled corticosteroids in the management of asthma, 2020 focused updates to the asthma management guidelines: A report from the national asthma education and prevention program coordinating committee expert panel working group. Satisfaction. elvitegravir/cobicistat/emtricitabine/tenofovir DF will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. The excess mucus associated with asthma comes directly from the bronchial tubes as part of the inflammatory response, so lowering inflammation can help lessen mucus as well. However, in updated recommendations for asthma management issued in December 2020, the National Institutes of Health advised that for some people with mild to moderate persistent asthma, daily inhaler use may not be necessary.If you use an inhaler daily to manage asthma, talk to your healthcare provider about how the new guidelines might affect your treatment. Talk to your pediatrician if you have concerns about your child's growth. 2020 focused updates to the Asthma Management Guidelines: A report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group. Asmanex Website. Omalizumab (Xolair) is sometimes used to treat asthma triggered by airborne allergens. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Promote improved understanding about asthma and related diseases through educational programs and materials for our patients for other health care providers, and for the community Contact us The Mass General Brigham Asthma Center asthma@partners.org 1-800-972-7863 For an appointment, call 1-800-972-7863. 420 0 obj <>stream Dosages of inhaled corticosteroids varies widely depending on the specific drug, age, and the severity of asthma symptoms. See your health care provider right away if you have any unusual reaction. Smy L, Chan AC, Bozzo P, Koren G. Is it safe to use inhaled corticosteroids in pregnancy?. These common side effects of oral corticosteroids often are easy to manage or even eliminate altogether. Serious systemic symptoms may arise when the daily dosage is high1,000 to 1,500 micrograms (mcg) per dayincreasing the risk of the above side effects, plus: Most inhaled corticosteroids fall beneath this threshold. They reduce swelling and tightening in your airways. 12 years and older. Mometasone and Formoterol Dulera 12 and older 100/5, 200/5 mcg per inhalation (120) What is aspirin-exacerbated respiratory disease (AERD)? Max 12 puffs/day. https://www.aaaai.org/Tools-for-the-Public/Drug-Guide. So this means it will dialate your airway, make it bigger so air can pass thru it easier. Copyright 2023 by RxList Inc. An Internet Brands company. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. Comment: Corticosteroids may increase hypokalemic effect of loop diuretics. Accessed May 13, 2021. FDA requires Boxed Warning about serious mental health side effects for asthma and allergy drug montelukast (Singulair); Advises restricting use for allergic rhinitis. Use Caution/Monitor. It may be used either with or instead of a SABA. Age 12 and older. Coadministration of quinolone antibiotics and corticosteroids may increase risk of tendon rupture. Inhaled Corticosteroids. Flovent (fluticasone propionate); Qvar (beclomethasone); Asmanex (mometasone); and Aerospan (flunisolide). It's often necessary to try several to see how they work or if you experience any side effects. Fluticasone Furoate 100 mcg Pulmicort Respules Anyone who gets an injection of this drug should be monitored closely by health care professionals in case of a severe reaction. Although theophylline isn't used much anymore, it can be helpful for nighttime asthma symptoms. Advair Diskus 100/50, 250/50 and 500/50 are for age 12 and older. 2020 focused updates to the asthma management guidelines: A report from the national asthma education and prevention program coordinating committee expert panel working group. Always consult your healthcare provider. The drug information provided is intended for reference only and should not be used as a substitute for medical advice. What Are Possible Side Effects of Asmanex? Beclovent Vanceril Q-Var 84-336 mcg (2-8 puffs42 mcg) Properly discard this product when it is expired or no longer needed. Prednisone withdrawal: Why taper down slowly? endstream endobj startxref Originally prescribed product (below): gg gg mcg g g x x g g g g g g g Small Particle Controllers: Aerospan Alvesco Qvar 80mcg Can be exchanged Pulm Ther (2017) 3:1. doi:10.1007/s41030-017-0043-5, Cloutier MM, Baptist AP, Blake KV, et al. Use Caution/Monitor. mometasone inhaled decreases effects of corticorelin by Other (see comment). These antibodies signal your immune system to release chemicals into your bloodstream, causing a reaction that leads to allergy and asthma symptoms. Comment: Corticosteroids may increase hypokalemic effect of loop diuretics. These medications block the effects of leukotrienes, immune system chemicals that cause asthma symptoms. Corticosteroid with potent anti-inflammatory properties; exerts effects on various cells, including mast cells and eosinophils; also exerts effects on inflammatory mediators (eg, histamine, eicosanoids, leukotrienes, cytokines). Do not increase your dose, use this drug more often, or stop using it without first consulting your doctor.If you are regularly taking a different corticosteroid by mouth (such as prednisone), you should not stop taking it unless directed by your doctor. You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088. What is the difference between flovent hfa and flovent diskus? 7 . 7.0 out of 10 from a total of Eosinophils release substances, called cytokines, which cause inflammation. mometasone inhaled increases toxicity of amphotericin B deoxycholate by Other (see comment). Increases riak for systemic corticosteroid side effects. Use Caution/Monitor. Remove the cap. Serious - Use Alternative (1)mometasone inhaled increases toxicity of desmopressin by Other (see comment). Discuss the risks and benefits with your doctor.It is unknown if this drug passes into breast milk. lopinavir increases levels of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Some side effects result when the medication and/or propellant comes in contact with tissues in the mouth and throat. Flonase (fluticasone) and Nasonex (mometasone) are about the same. Flovent may also interact with conivaptan, diclofenac, imatinib, isoniazid, antibiotics, antidepressants, and heart or blood pressure medications. A newer class of biologic drugs has been developed to target specific substances produced by certain immune system cells. I have 2 questions, is the strength of asmanex 110 comparable to flovent 110. is flovent diskus small enough to get into the small airways. Mayo Clinic does not endorse any of the third party products and services advertised. Long-term side effects can include cataracts, thinning bones (osteoporosis), muscle weakness, decreased resistance to infection, high blood pressure and reduced growth in children. People report fewer asthma symptoms and better lung function when they take it every day. Maximum is 360 mcg twice a day. This drug is available at a middle level co-pay. Combivent is the brand name for albuterol and ipratropium bromide (Atrovent). Copyright 2023 by RxList Inc. An Internet Brands company. Monitor Closely (1)atazanavir increases levels of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Often called rescue medications, they can ease worsening symptoms or stop an asthma attack in progress. Use Caution/Monitor. Accessed May 12, 2022. clarithromycin will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. mometasone inhaled increases toxicity of furosemide by Other (see comment). Use Caution/Monitor. 1-2 puffs twice a day. Some examples of ICSs are beclomethasone dipropionate (Qvar), budesonide (Pulmicort), fluticasone propionate (Flovent), mometasone furoate (Asmanex), or triamcinolone acetonide (Azmacort). commonly, these are generic drugs. Are Nebulizers Better Than Inhalers for COPD and Asthma? commonly, these are "non-preferred" brand drugs or specialty You have a lot of factors to weigh when selecting the right inhaled corticosteroid for your asthma. Eur Respir J. To reduce the likelihood of adverse effects, healthcare providers should screen for possible drug interactions. This website also contains material copyrighted by 3rd parties. Use Caution/Monitor. Theophylline SIDE EFFECTS: See also Precautions section.Dry/irritated throat, hoarseness, or coughing may occur as your body adjusts to the medication. Access your plan list on any device mobile or desktop. in combination with Mometasone Asmanex Twisthaler (DPI), 60 doses. 80mcg Flovent Diskus are for use in patients age 4 years and older . The older, first generation INCSs (beclomethasone dipropionate, triamcinolone acetonide, flunisolide, budesonide) have a significantly higher systemic bioavailability than the second generation INCSs (ciclesonide, fluticasone furoate, fluticasone propionate, mometasone furoate . LKY1gncIaf^\YO . Prescriber should designate the exact strength 80/4.5 or 160/4.5. Flovent (fluticasone propionate) is a steroid used to prevent asthma attacks. Increased risk of Cushing's syndrome or adrenal suppression. Vilanterol 25 mcg. mometasone inhaled and levofloxacin both increase Other (see comment). mometasone/formoterol (Dulera), and fluticasone furoate/vilanterol (Breo Ellipta) should only be prescribed for patients not adequately controlled on a single-agent long-term asthma control medication, such as an inhaled corticosteroid (ICS), or whose disease severity clearly . This medicine is sometimes used together with steroid medicine taken by mouth. Dulera Website. Li JTC (expert opinion). 180mcg (Flovent) 100-250 >250-500 >500 2000 Mometasone (Asthmanex) 200 >200-400 >400-800 800 References: 1 E-CPS. There is a problem with These biological drugs target eosinophils and cytokines, reducing their numbers within the body and lowering inflammation. Potential for increased toxicity. Fluticasone (flovent ) Mometasone furoate (asmanex ) Triamcinolone (azmacort ) Adult (usual): inhale: 2 puffs 3 to 4 times a day or 4 puffs twice a day. Inhaled corticosteroids are intended to be used regularly, likely over the course of many years. Advair HFA 230/21 Thank you, {{form.email}}, for signing up. When growth is impaired, it's usually by less than half an inch. The right inhaler is the one that works for you. Dose: High . Both Advair contains fluticasone, a steroid, and salmeterol, a long acting bronchodialtor. Flovent HFA may also be used for purposes not listed in this medication guide. If you have allergies, your immune system identifies a harmless airborne substance such as pollen, dust mites and pet dander as being harmful. Agache I, et al. saquinavir will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. In a trial comparing budesonide 400 mcg twice daily to various doses of mometasone furoate twice daily, the FEV1 was significantly improved from baseline in the mometasone furoate 200 and 400 mcg treatment groups compared to the budesonide treatment group. Asmanex (mometasone) is an inhaler so it allows for more direct delivery of medicine to the lungs compared to a pill. Systemic side effects are possible but uncommon with inhaled steroids. %PDF-1.6 % Use Caution/Monitor. You may opt-out of email communications at any time by clicking on This medication works best if used at evenly spaced intervals. mometasone inhaled increases toxicity of torsemide by Other (see comment). Comment: Agents used to treat airway disease may enhance the toxic effect of inhaled loxapine. Monitor Closely (1)lopinavir increases levels of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Treating Long QT Patients Who Have Asthma. With your health care provider, create a written detailed plan for taking long-term control medications and for managing an asthma attack.